Daniel Rose

AI-driven de novo molecular design offers a promising route to accelerate early-stage drug discovery by generating novel ligands directly within target protein binding pockets. We present NEAT-POCKET, a pocket-conditioned extension of the autoregressive NEAT model for 3D molecular generation.

On May 7, the Federal Trade Commission (FTC) published a final rule banning the enforcement of nearly all noncompete clauses in employment agreements nationwide (89 FR 38342). This new rule will have sweeping effects across all sectors of the economy, if it survives court challenges that have already been filed (see, e.g., Chamber of Commerce of the United States of America v. FTC, 6:24-cv-00148 (E.D. Tex., April 24, 2024). What Is the New Rule?

In the vibrant and ever-evolving marine fuels market, a myriad of roles contribute to the seamless operation and success of the industry. However, amidst the bustling activity and the spotlight often shining on traders and suppliers, there lies an unsung hero whose efforts are pivotal yet frequently overlooked: the Bunker Credit Manager. As a former credit manager myself, I wanted to shed some light on this critically important, but often underappreciated role.