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Daniel Selma Herrador on Muck Rack

Daniel Selma Herrador

As seen in: BioRxiv
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Articles

Morphogenesis-on-chip: A minimal in vitro assay for cell intercalation highlights the importance of interfacial tension and migratory forces

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By Artur Ruppel, Vladimir Misiak, Sadjad Arzash, Daniel Selma Herrador
| BioRxiv
Abstract Cell intercalation, the dynamic exchange of cellular neighbors, is fundamental to embryonic morphogenesis, tissue homeostasis, and wound healing. Despite extensive study in complex tissues, the minimal mechanical requirements driving intercalation remain poorly understood due to confounding tissue level interactions. Here, we present a novel morphogenesis-on-chip assay utilizing micropatterned cell quadruplets.
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