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Daniel Youssef Bargieri on Muck Rack

Daniel Youssef Bargieri

As seen in: Nature, The Lancet
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Articles

Salvage of host-derived geranylgeraniol limits fosmidomycin efficacy in murine Plasmodium berghei malaria

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By Ignasi Bofill Verdaguer, Cathy Chen, Mauricio Mazzine Filho, Matheus Felipe Santos, Gabriela Castro, Lydia Fumiko Yamaguchi, Sandra de Oliveira, Manoel Aparecido Peres, Agustín Hernández, Thales Kronenberger, Daniel Youssef Bargieri, Claudia Blanes Angeli, Giuseppe Palmisano, Luis Izquierdo, Luciana Azevedo, Audrey John, Alejandro Miguel Katzin, Marcell Crispim, Dana Hodge
| Nature Verified
Abstract Despite promising preclinical activity, fosmidomycin has shown limited clinical efficacy against malaria. It inhibits the methylerythritol 4-phosphate (MEP) pathway, which supplies precursors for farnesyl and geranylgeranyl pyrophosphate (FPP, GGPP) synthesis and protein prenylation.
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Protection against COVID-19: beyond antibodies

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By Daniel Youssef Bargieri
| The Lancet Verified
The COVID-19 pandemic has exposed the deep inequalities of our times. Differences in behaviour, political will, and technological capacity between affected countries have contributed to distinct outcomes. 1 Bambra C Riordan R Ford J Matthews F The COVID-19 pandemic and health inequalities. J Epidemiol Community Health.
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