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Danielle Guez-Barber on Muck Rack

Danielle Guez-Barber

As seen in: BioRxiv
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Articles

Microglial depletion worsens lesion in female but not male C57BL/6J mice after P10 hypoxia-ischemia

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By Danielle Guez-Barber, Sofia Nicolayevsky, Kaya Johnson, Sanghee Yun
| BioRxiv
Abstract Background: Rodent models for perinatal hypoxic ischemic (HI) encephalopathy have reported sex differences such as the same injury causing larger lesions in the brains of males compared to females. Microglia, the resident immune cells of the brain that have sex-dependent developmental trajectories and gene expression patterns, likely play a different role in females and males following HI.
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Microglial depletion worsens lesion in female but not male C57BL/6J mice after P10 hypoxia-ischemia

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By Danielle Guez-Barber, Kaya Johnson, Sanghee Yun, Sofia Nicolayevsky
| BioRxiv
Abstract Background: Rodent models for perinatal hypoxic ischemic (HI) encephalopathy have reported sex differences such as males having larger brain lesions than females after the same injury. Microglia, the resident immune cells of the brain that have distinct developmental trajectories and gene expression patterns by sex, likely play a different role in males and females following HI.
Open in Who Shared Issue with article?

Female and male microglia are not different in the dentate gyrus of postnatal day 10 mice

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By Lorianna Colon, Dana Raphael, Danielle Guez-Barber, Max Wragan
| BioRxiv
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