Danqun Zhang

Abstract Psoriasis is a common chronic inflammatory skin disease that significantly affects patients’quality of life. There is no cure for psoriasis, and available treatments are not completely effective. We have previously found that hydroxytyrosol (HT) has anti-psoriatic effects in vitro. In the present study, we aimed to investigate the therapeutic effects of HT on psoriasis in vivo and to explore the underlying mechanisms.

1 Introduction Melanoma, a highly aggressive form of skin cancer, poses significant challenges due to its propensity for immune evasion and rapid progression. One of the critical factors contributing to melanoma's aggressiveness is its high mutational burden, which enhances its immunogenicity and influences the interaction between tumor cells and immune cells [1, 2].