Danushka Marapana on Muck Rack

Danushka Marapana

Melbourne
As seen in: Nature, Science Magazine
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Articles

GID/CTLH E3 ligase complex control cell fate programs for sexual development of Plasmodium falciparum

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By Danushka Marapana, Sash Lopaticki, Simon A. Cobbold, Niall Geoghegan, Sachin Khurana, Stephen W. Scally, Peter Hickey, Vineet Vaibhav, Sukhdeep K Spall, Jumana Yousef, Laura F Dagley, Christopher D. Goodman, Anton Cozijnsen, Geoffrey I. McFadden, Kelly L. Rogers, Aaron Jex, David Komander, James McCarthy, Christopher J. Tonkin, Matthew Dixon, Alan F. Cowman, Balu Balan, Kitsanapong Reaksudsan, Niva Jayakrishnan
| Nature Verified
Abstract Transmission of the malaria parasite Plasmodium falciparum requires the formation of specialised sexual cells called gametocytes. A hallmark of P. falciparum gametocyte development is its long duration, during which the parasite undergoes dramatic cellular remodelling including morphological, physiological and metabolic changes which result in the formation of a transmission ready, stage V gametocyte.
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Uncovering the ART of antimalarial resistance

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By Danushka Marapana, Alan F. Cowman
| Science Magazine Verified
Download and print this article for your personal scholarly, research, and educational use. Buy a single issue of Science for just $15 USD.
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The Metabolite Repair Enzyme Phosphoglycolate Phosphatase Regulates Central Carbon Metabolism and Fosmidomycin Sensitivity in Plasmodium falciparum

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By Mark Richardson, Danushka Marapana, Tony Triglia, Laure Dumont
| asm.org
Research Article | Host-Microbe Biology Laure Dumont, Mark B. Richardson, Phillip van der Peet, Danushka S. Marapana, Tony Triglia, Matthew W. A. Dixon, Alan F. Cowman, Spencer J. Williams, Leann Tilley, Malcolm J. McConville, Simon A. Cobbold L. David Sibley, Editor DOI: 10.1128/mBio.02060-19 ABSTRACT Members of the haloacid dehalogenase (HAD) family of metabolite phosphatases play an important role in regulating multiple pathways in Plasmodium falciparum central carbon metabolism. We show that the P.
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