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Danyang Zhao on Muck Rack

Danyang Zhao

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Articles

Overexpression of Circular RNA circTTN Promotes Ferroptosis in Sepsis-Induced Cardiomyopathy

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By Qian Lei, Danyang Zhao, Zhen Wei
| Wiley Online Library Verified
1 Introduction Sepsis is defined as the dysfunction of a system or organ due to the body's dysregulated response to inflammatory processes [1, 2]. If not identified promptly and addressed appropriately, it can result in shock, multiple organ failure and potentially fatal outcomes [3, 4]. With the characteristics of high morbidity and mortality, it has become the first major cause of death in acute and critical patients [5, 6].
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Genomic and genetic dissection of drought tolerance in a resilient wheat germplasm JIN50

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By Jingchen Lin, Chenji Zhang, Zehui Liu, Jinpeng Li, Qun Yang, Wei Chu, Debiao Liu, Lei Zhang, Danyang Zhao, Xiao P Peng, Mingming Xin, Yingyin Yao, Weilong Guo, Huiru Peng, Chaojie Xie, Zhongfu Ni, Qixin Sun, Zhaorong Hu, Wanghongan Jia, Huitao An
| Nature Verified
Abstract Global climate change intensifies drought threats to wheat productivity, necessitating genetic enhancement of drought resistance. We present a high-quality genome assembly of drought-resistant wheat genotype Jin50LP82 (JIN50; contig N50 = 50.24 Mb) and conduct genomic analyses across 31 wheat genomes and 196 germplasm samples, revealing 430,739 structural variants.
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Soluble uric acid suppresses neutrophil-mediated host defense in sepsis

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By Qiubo Li, Kailey Flora, Carolin Charlotte Wendling, Fengjun Zhang, Liang Chang, Danyang Zhao, Oliver Soehnlein, Stefanie Steiger, Juliane Anders, Louisa Ehreiser, Raimund Vogl
| Nature Verified
Abstract Neutrophils are essential for host defense and inflammation, yet their dysfunction is a hallmark of acquired immunodeficiency in kidney disease, contributing to increased susceptibility to infections such as peritonitis, sepsis, and pneumonia. We speculated that impaired renal clearance of the metabolite soluble uric acid (sUA) accounts for neutrophil dysfunction.
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