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Daoan Wang

As seen in: Wiley Online Library, ACS Publications
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Articles

Design and Engineering of an Artificial Bifunctional N -Deacetylase/ N -Sulfotransferase for the Biosynthesis of N -Sulfated Heparosan

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By Xintong Xi, Ruirui Xu, Daoan Wang
| Wiley Online Library Verified
1 Introduction Heparin is a naturally occurring, highly sulfated glycosaminoglycan that represents the most extensively used anticoagulant in clinical medicine. Beyond its anticoagulant function, heparin exhibits diverse pharmacological activities, including antithrombotic, antitumor, anti-inflammatory, and antiviral effects [1-4]. Traditionally, heparin is extracted from natural animal tissues, especially the porcine intestinal mucosa.
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Efficient Expression of an Engineered Heparan Sulfate 2-O-Sulfotransferase with Improved Catalytic Properties

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By Linpei Zhang, Wuxia Chen, Daoan Wang, Xintong Xi
| ACS Publications
Biotechnology and Biological TransformationsMay 14, 2025 Wuxia Chen The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China The Science Center for Future Foods, Jiangnan University, Wuxi 214122, China Jiangsu Province Basic Research Center for Synthetic Biology, Jiangnan University, Wuxi 214122, China State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China Daoan Wang The Key Laboratory...
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Efficient Expression of an Engineered Heparan Sulfate 2-O-Sulfotransferase with Improved Catalytic Properties

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By Wuxia Chen, Daoan Wang, Xintong Xi, Linpei Zhang
| dx.doi.org
Biotechnology and Biological TransformationsMay 14, 2025 Wuxia Chen The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China The Science Center for Future Foods, Jiangnan University, Wuxi 214122, China Jiangsu Province Basic Research Center for Synthetic Biology, Jiangnan University, Wuxi 214122, China State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China Daoan Wang The Key Laboratory...
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