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Darshna Rambhia on Muck Rack

Darshna Rambhia

As seen in: Frontiers in Immunology
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Articles

Type 17 T-cell subset divergence in hidradenitis suppurativa versus psoriasis: a comparative single-cell transcriptomic analysis

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By Nayoung Park, Jongeun Lee, Dayeon Kim, Jaebum Kim, Wei Zhou, Junyue Cao, James Krueger, Younhee Ko, Jaehwan Kim, Darshna Rambhia
| Frontiers in Immunology
Abstract Background: IL-17-producing Type 17 T (T17) cells are central drivers of inflammation in both psoriasis and hidradenitis suppurativa (HS), as evidenced by the clinical efficacy of IL-17-targeting therapies. However, therapeutic responses differ substantially between diseases, raising the possibility that the composition and regulation of T17 states are disease context dependent.
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