Daryl Conner

Abstract Non-tuberculous mycobacteria are emerging pathogens with high intrinsic drug resistance. Among these, Mycobacterium abscessus is particularly refractory owing to its extensive array of resistance mechanisms. Here we introduce florfenicol amine (FF-NH2), a major metabolite of the antibiotic florfenicol, which acts as a prodrug with narrow-spectrum activity against M. abscessus−chelonae complex species. FF-NH2 leverages intrinsic M.

For the past twelve months, my writing has focused on exploring what we, as change professionals, can do to deliver exceptional value to those we serve. Of the two areas that demand advancement, “what we do” and “who we are”, I have given special attention to the role who we are plays in being viewed as an indispensable resource. The text that follows is a brief summary of what I have uncovered.

The presentation appeared to be going very well. As the process redesign team unveiled the new set of revenue-accounting processes to its peers and to the first-level accountants, the discussion in the room had been surprisingly positive--everyone seemed to agree that the old combination of patchwork processes and ancient technology was badly in need of repair.