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David Barnes-Seeman

As seen in: BioRxiv
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Articles

PSMtags improve peptide sequencing and throughput in sensitive proteomics

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By Harrison Specht, Maddy Yeh, Sarah N. Sipe, David Barnes-Seeman
| BioRxiv
Abstract Mass spectrometry-based proteomics enables comprehensive characterization of protein abundance, function, and interactions. Label-free approaches are simple to implement but challenging to scale to thousands of samples per day. Multiplexed techniques, such as plexDIA, can address these limitations but remain restricted by the lack of mass tags optimized for data-independent acquisition (DIA) workflows.
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