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David Calzón Lozano on Muck Rack

David Calzón Lozano

As seen in: Nature, MDPI, Periodista Digital
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Articles

Targeting ELOVL6 to disrupt c-MYC driven lipid metabolism in pancreatic cancer enhances chemosensitivity - Nature Communications

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By ANA GARCÍA Verified, Ana Garcia, Maria Ferrer Aporta, German Vallejo Palma, David Calzón Lozano, Raul Velasco, Raul Torres-Ruiz, Sandra Rodriguez-Perales, Jonas Dehairs, Johannes V. Swinnen, Juan Carlos Garcia-Canaveras, Agustin Lahoz, Francisco Monroy, Marina Alonso Riaño, Alberto Mora Perdiguero, Carlos del Pozo-Rojas
| Nature Verified
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer with a 12% survival rate, highlighting the need for novel therapies. c-MYC overexpression, driven by upstream mutations and amplifications, reprograms tumor metabolism and promotes proliferation, migration and metastasis. This study identifies ELOVL6, a fatty acid elongase regulated by c-MYC, as a potential therapeutic target.
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Lymph Vessels Associate with Cancer Stem Cells from Initiation to Malignant Stages of Squamous Cell Carcinoma

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By Anna Cazzola, Dennis Menne, David Calzón Lozano, Raquel Dávila Pedrera
| MDPI
4. Materials and Methods 4.1. Human and Mouse SCC Samples Human tissues were purchased from US Biomax now TissueArray (TMA SK-801c, TissueArray, Derwood, MD, USA) or previously donated by Robert Loewe from the Department of Dermatology, Medical University of Vienna [44]. The analyzed mouse samples were derived from mice described in a prior study [44].
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Sexo salvaje: Así se lo montan los gorilas

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By David Calzón Lozano
| Periodista Digital Verified
Así se lo montan los gorilas… imágenes muy bonitas. Sólo dos especies de gorilas quedan hoy en el mundo y ambas en Africa: el Gorila Oriental y el Gorila Occidental, cada especie tiene una pareja de subespecies, lo cual ayuda aún más a fomentar la formación de pequeños grupos de individuos. Los gorilas pueden ser agresivos cuando se sienten que ellos o su familia están en peligro.
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