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David Lewis on Muck Rack

David Lewis

Australia
As seen in: Color Research & Application, Nature, The Guardian, The Washington Post, Los Angeles Times, New Phytologist, PLOS, The Atlantic, Frontiers, MDPI and
Bay Area native. Executive Director of Save The Bay. Tweets are my own.
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Articles

Multiscale in vivo imaging of tumor evolution using a germline conditional triple-reporter mouse

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By Ximena Raffo-Iraolagoitia, Stephanie May, David Stevenson, Lynn McGarry, Jayanthi Anand, Dmitry A. Soloviev, Gavin Brown, Colin Nixon, Chrysa Kapeni, Karen Blyth, Thomas Bird, Douglas Strathdee, Scott Lyons, Gilbert O. Fruhwirth, Leo M. Carlin, David Lewis, Abdullah Alyamani, Agata Mackintosh, Maike De La Roche
| Nature Verified
Abstract Imaging reporter genes are essential tools in cancer research for monitoring tumor evolution, cell dissemination, gene activation and treatment response. However, germline reporter models typically rely on single imaging modalities operating over limited spatial scales.
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Toward a Pluralistic Model for the Schizophrenia Spectrum—Dopamine and Beyond

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By Matcheri S. Keshavan, Henry A. Nasrallah, Anissa Abi-Dargham, Anthony A. Grace, Daniel C Javitt, David Lewis, Stephen Marder, Jonathan Meyer, Robin Murray, Dost Ongur Verified, Stephen Stahl, Rajiv Tandon
| JAMA Psychiatry Verified
Toward a Pluralistic Model for the Schizophrenia Spectrum—Dopamine and Beyond Key Points Question Are schizophrenia-related disorders best explained by a dopaminergic final common pathway or by a pluralistic model of multiple interacting neurochemical mechanisms? Findings Pharmacologic and neuroimaging evidence shows dopaminergic dysregulation in the associative striatum underlying psychosis.
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Toxicology-informed sequencing to optimise cancer therapy - Authors’ reply

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By David Lewis, Simon Rule
| The Lancet Verified
We thank Gang Lv and colleagues for the response to our study.1 We agree that minimal residual disease (MRD) monitoring could help to optimise the treatment of mantle-cell lymphoma with ibrutinib and other Bruton tyrosine kinase (BTK) inhibitors. However, no study comparing outcomes of continuous use of BTK inhibitors versus an MRD-driven approach has yet been reported.
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