O.Keene, D.Wright, and C.Fletcher, “Commentary on Fleming et al. “A Perspective on the Appropriate Implementation of ICH E9(R1) Addendum Strategies for Handling Intercurrent Events”,” Statistics in Medicine45, no. 6-7 (2026): e70453, https://doi.org/10.1002/sim.70453. Conflicts of Interest O.N.K. is an independent consultant to the pharmaceutical industry. D.W. and C.F. are employed by pharmaceutical companies as declared above.