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USPTO Issues Foundational Patent for Leptin Replacement in Anorexia Nervosa, Exclusively Licensed to Zula Therapeutics
Method-of-use patent gives Zula an exclusive position in leptin replacement for anorexia nervosa We are grateful to the patients, institutions, and funders whose support has allowed us to demonstrate the novelty, symptom improvement, and safety of leptin as a treatment for anorexia thus far.” — Professor Johannes Hebebrand, University of Duisburg-Essen, co-inventor BOSTON, MA, UNITED STATES, August 11, 2026 / EINPresswire.com/ -- Zula Therapeutics, Inc.
Use of Bayesian decision analysis to maximize value in patient-centered randomized clinical trials in Parkinson’s disease
6. Discussion In this article, we modify the traditional 5% significance level used in standard RCT designs to better reflect patient preferences and their medical needs. We quantify the loss of value to public health associated with false approvals and rejections, then use BDA to determine the optimal significance level and sample size that minimize this loss, and thereby, maximize this value.
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