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David Wishart on Muck Rack

David Wishart

Seattle
As seen in: Nature, Wiley Online Library, The London Standard, Chicago Tribune, MDPI, ACS Publications, The Boston Globe, Yahoo, The Press and Journal, North Shore News and
30 years writing about the best ships for leading outlets in Europe and North America
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Articles

Multiomics characterization of acute child illness and mortality in Africa and South Asia

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By Camilo A. Espinosa, James M. Njunge, Kirkby D Tickell, Abdoulaye Diallo, Amran Gazi, Zaubina Kazi, Emily Yoshioka, Caroline Tigoi, Moses Mburu, Moses Ngari, Narshion Ngao, Bonface M. Gichuki, Anna Mitchel, Jessica Williams, Nebojsa Janjic, Rupasri Mandal, Benjamin Jenkins, Hilary P. Browne, Yan Shao, Timothy J. Rozday, Mark Stares, Nicholas Dawson, Eloise Berson, Alan Chang, Yeasul Kim, Samson Mataraso, Chi-Hung Shu, Thanaphong Phongpreecha, Lei Xue, Ali Saleem, Benson O Singa, Tahmeed Ahmed, Wieger Voskuijl, David Wishart, Eric R. Houpt, Jie Liu, Asad Ali, Ezekiel Mupere, Mohammod Jobayer Chisti, Robert H. J. Bandsma, Trevor D. Lawley, Albert Koulman, Christina L. Lancioni, Nima Aghaeepour, James A Berkley, Judd Walson, Elisha Omer, Wilson Gumbi, Joseph Gogain
| Nature Verified
Abstract Childhood illnesses from infectious diseases in low- and middle-income countries contribute substantially to the global under-five mortality. Many hospitalized children experience incomplete recovery, readmission, and post-discharge mortality despite guideline-directed care. However, targeted interventions remain elusive due to limited understanding of underlying mechanisms.
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A resource to empirically establish drug exposure records directly from untargeted metabolomics data - Nature Communications

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By Haoqi Zhao, Kine Eide Kvitne, Vincent Charron-Lamoureux, Wout Bittremieux, Robin Schmid, Santosh Lamichhane, Yasin El Abiead, Mohammadsobhan S. Andalibi, Helena Mannochio-Russo, Nicole E. Avalon, Lluís Corominas, Ronald J Ellis, Alan K Jarmusch, Sarolt Magyari, Ipsita Mohanty, Andrés Cumsille, Prajit Rajkumar, Dylan Ross, Crystal Wang, Simone Zuffa, David Wishart, Rima Kaddurah-Daouk, Manuela Raffatellu, Karsten Zengler, Tomáš Pluskal, Libin Xu, Rob Knight Verified, Shirley M Tsunoda, MacKenzie Bryant
| Nature Verified
Abstract Despite extensive efforts, extracting medication exposure information from clinical records remains challenging. To complement this approach, here we show the Global Natural Product Social Molecular Networking (GNPS) Drug Library, a tandem mass spectrometry (MS/MS) based resource designed for drug screening with untargeted metabolomics.
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Discovery of metabolites prevails amid in-source fragmentation - Nature Metabolism

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By Adriano Rutz, Simone Zuffa, Shipei Xing, Corinna Brungs, Michael Witting, Tomáš Pluskal, Wout Bittremieux, Sebastian Böcker, Warwick Dunn, Roger G. Linington, David Wishart, Jean-Luc Wolfender, Oliver Fiehn, Nicola Zamboni
| Nature Verified
The detectable ‘dark metabolome’, or unannotated signals in untargeted metabolomics, has become a focal point of debate. The recent Correspondence by Giera et al.1 published in Nature Metabolism argued that most unannotated signals in liquid chromatography–tandem mass spectrometry (LC-MS/MS) data are in-source fragments (ISFs), and hence measurement artefacts rather than new molecules.
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