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Articles by de Borst
Recanalization and Recurrent Stroke After Cervical Artery Dissection Developing Appropriate Clinical Guidance?
Get full access to this article View all available purchase options and get full access to this article. References 1. Romoli M, Muppa J, Lee EM, et al. Recalanization after acute cervical artery dissection: a multicenter international study. Neurology. 2026;107(9):e218566. 2. van Laarhoven CJHCM, Arnold M, Danilova M, et al. Delayed development of aneurysmal dilatations in patients with extracranial carotid artery dissections. Eur J Vasc Endovasc Surg. 2022;64(6):595-601. 3.
The prevalence and associations of stroke history with self-reported sleep disturbances in China: a nationwide cross-sectional study
Background Sleep is essential for stroke prognosis and recovery. While stroke history has been associated with sleep disturbances, evidence from China remains limited. This study aimed to characterize the prevalence of multiple sleep disturbances and to examine their associations with stroke history based on the China Nutrition and Health Surveillance 2015–2017. Methods 157,135 respondents were included in the current study. Stroke history was defined as being first diagnosed over one year ago.
Natriuretic Response to an Acute Oral Potassium Load in Healthy Individuals and Patients with Chronic Kidney Disease: A Randomized Controlled Trial
The health benefits of dietary potassium have been linked to potassium-induced natriuresis. However, it is unknown whether potassium loading in patients with chronic kidney disease (CKD) induces natriuresis and to which degree it increases plasma potassium. We hypothesize that potassium-induced natriuresis remains intact and that potassium loading is safe in patients with CKD.
Calciphylaxis Diagnosis, Management and Future Directions: a Comprehensive Update on behalf of the European Renal Association CKD-MBD Working Group
PDF Split View Sharon Huish, Sacha Moore, Carlo Alfieri, Antonio Bellasi, Daniel Cejka, Martin H de Borst, Juan Miguel Diaz-Tocados, Pietro Manuel Ferraro, Maria Fusaro, Mathias Haarhaus, Ditte Hansen, Mehmet Kanbay, Markus Ketteler, Smeeta Sinha, Calciphylaxis Diagnosis, Management and Future Directions: a Comprehensive Update on behalf of the European Renal Association CKD-MBD Working Group, Clinical Kidney Journal, 2025;, sfaf338, https://doi.org/10.1093/ckj/sfaf338 Close calcific uraemic...
Pathophysiology of chronic kidney disease-mineral bone disorder (CKD-MBD): from adaptive to maladaptive mineral homeostasis
Chronic kidney disease–mineral bone disorder (CKD-MBD) is a complex syndrome frequently observed in individuals with impaired renal function [1–4]. It encompasses a spectrum of interrelated abnormalities in mineral metabolism, bone structure and cardiovascular calcification, and is associated with low quality of life, reduced life expectancy and higher healthcare expenditures [1, 2, 5].
Does Correction of Secondary Hyperparathyroidism with Extended-Release Calcifediol Provide Renoprotection?
Keywords: Chronic kidney disease-mineral and bone disorder, Parathyroid hormone, Kidney function, Calcifediol Chronic kidney disease-mineral and bone disorder (CKD-MBD) is characterized by skeletal and cardiovascular abnormalities, including CKD-associated osteoporosis and vascular calcification. It is more likely to occur with more advanced CKD and has been linked with a reduced quality of life and premature mortality. A major biochemical hallmark of CKD-MBD is secondary hyperparathyroidism.
Higher skeletal muscle mass associates with higher measured glomerular filtration rate in healthy individuals
Accepted manuscripts are PDF versions of the author’s final manuscript, as accepted for publication by the journal but prior to copyediting or typesetting. They can be cited using the author(s), article title, journal title, year of online publication, and DOI. They will be replaced by the final typeset articles, which may therefore contain changes. The DOI will remain the same throughout.
Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits
Hyppää sisältöön Keaton, Jacob M.; Kamali, Zoha; Xie, Tian; Vaez, Ahmad; Williams, Ariel; Goleva, Slavina B.; Ani, Alireza; Evangelou, Evangelos; Hellwege, Jacklyn N.; Yengo, Loic; Young, William J.; Traylor, Matthew; Giri, Ayush; Zheng, Zhili; Zeng, Jian; Chasman, Daniel I.; Morris, Andrew P.; Caulfield, Mark J.; Hwang, Shih-Jen; Kooner, Jaspal S.; Conen, David; Attia, John R.; Morrison, Alanna C.; Loos, Ruth J.
Inter- and Intra-observer Agreement of the Peripheral Arterial Calcium Scoring System in Patients Undergoing (Infra)Popliteal Endovascular Interventions | CardioVascular and Interventional Radiology
Abstract Peripheral arterial calcification is an important predictor of outcomes after both conservative and endovascular treatment. Digital subtraction angiography (DSA)-based calcification scores are limited by low sensitivity and inter-observer agreement. The Peripheral Arterial Calcium Scoring System (PACSS) assesses the severity of target lesion calcification. The newly introduced modified PACSS (mPACSS) also evaluates target vessel calcification.
Vitamin C deficiency after kidney transplantation: a cohort and cross-sectional study of the TransplantLines biobank - European Journal of Nutrition
Abstract Vitamin C deficiency is associated with excess mortality in kidney transplant recipients (KTR). We aim to evaluate plasma vitamin C status at different post-transplantation moments and assess the main characteristics associated with vitamin C deficiency in KTR. Plasma vitamin C was assessed in 598 KTR at 3-, 6-, 12-, 24-, and 60-months post-transplantation, 374 late KTR with a functioning graft ≥ 1 year, and 395 potential donors.
Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits
Keaton, J. M. et al. (2024) Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits. Nature Genetics, (doi: 10.1038/s41588-024-01714-w) (PMID:38689001) (Early Online Publication) Text 322757.pdf - Published Version Available under License Creative Commons Attribution. 3MB Abstract Hypertension affects more than one billion people worldwide.
[2403.19426] A multi-step calibration strategy for reliable parameter determination of salt rock mechanics constitutive models
[Submitted on 28 Mar 2024] Title:A multi-step calibration strategy for reliable parameter determination of salt rock mechanics constitutive models View a PDF of the paper titled A multi-step calibration strategy for reliable parameter determination of salt rock mechanics constitutive models, by Herm\'inio T.
Effect of high in comparison to low dairy intake intervention on markers of bone and cartilage remodeling and phosphate metabolism in healthy adults with overweight | European Journal of Nutrition
Abstract In the ageing population, issues with bone and joint health are highly prevalent. Both beneficial and potential risks of dairy products on bone and joint health are reported in epidemiological studies. Furthermore, the phosphorus (P) load from dairy could potentially lead to unfavorable changes in P metabolism. To investigate the effect of dairy intake on markers of bone and joint metabolism and P metabolism in an intervention study with high and low dairy intake.
Kidney phosphate wasting predicts poor outcome in polycystic kidney disease
Patients with ADPKD have disproportionately high levels of fibroblast growth factor-23 (FGF-23) for their CKD-stage with only a subgroup that develops kidney phosphate wasting. We assessed factors associated with phosphate wasting and hypothesize that it identifies patients with more severe disease and predicts disease progression. We included 604 patients with ADPKD from a multi-center prospective observational (DIPAK) cohort in 4 university medical centers in the Netherlands.
Kidney phosphate wasting predicts poor outcome in polycystic kidney disease
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease and is characterized by the development and expansion of bilateral cysts often leading to kidney failure [1].
Chronic kidney disease increases the susceptibility to negative effects of low and high potassium intake
Dietary potassium (K+) has emerged as a modifiable factor for cardiovascular and kidney health in the general population, but its role in people with chronic kidney disease (CKD) is unclear. Here, we hypothesize that CKD increases the susceptibility to negative effects of low and high K+ diets.
Chronic kidney disease increases the susceptibility to negative effects of low and high potassium intake
In the general population dietary potassium (K+) intake is ∼54 mmol/day [1] which is below the recommended intake of 90–120 mmol/day [2, 3]. Low dietary K+ intake is associated with salt-sensitive hypertension [4] and with a higher incidence of stroke [5], chronic kidney disease (CKD) [6] and mortality [7]. Increasing K+ intake through K+ supplementation or salt substitution decreases blood pressure and improves cardiovascular outcomes [5, 8].
Observational and Genetic Evidence for Bidirectional Effects Between Red Blood Cell Traits and Diastolic Blood Pressure
American Journal of Hypertension, Sep 2023 Previous studies have found associations of red blood cell (RBC) traits (hemoglobin and RBC count) with blood pressure; whether these associations are causal is unknown. This is a preview of a remote PDF: https://academic.oup.com/ajh/article-pdf/36/10/551/51272966/hpad061.pdf He, Zhen, Chen, Zekai, de Borst, Martin H, Zhang, Qingying, International Consortium of Blood Pressure, Snieder, Harold, Thio, Chris H L.
Observational and genetic evidence for bidirectional effects between red blood cell traits and diastolic blood pressure
Previous studies have found associations of red blood cell traits (hemoglobin and red blood cell count, RBC) with blood pressure; whether these associations are causal is unknown. We performed cross-sectional analyses in the Lifelines Cohort Study (n=167,785).
Sleep quality, fatigue, societal participation and health-related quality of life in kidney transplant recipients: a cross-sectional and longitudinal cohort study
Graft and patient survival among kidney transplant recipients (KTR) have improved drastically in the past decades [1]. As a result, increasing numbers of patients are living with a kidney transplant, for increasing periods of time. The subject of health-related quality of life (HRQoL) after transplantation thus keeps growing in importance, and rightfully receives increasing scientific attention.
Fasting ketone bodies and incident type 2 diabetes in the general population
3Division of Clinical Chemistry, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden 4Clinical Chemistry, Karolinska University Laboratory, Karolinska University Hospital, SE- 141 86 Stockholm, Sweden Correspondence to: Dr. Uwe Tietge, Division of Clinical Chemistry, Department of Laboratory Medicine (LABMED), H5, Alfred Nobels Alle 8, Karolinska Institutet, S-141 83 Stockholm, Sweden. Phone: +46852483723, email: uwe.tietge@ki.se Search for other works by this author on:
Effects of randomness and piezomagnetic coupling on the appearance of stop-bands in heterogeneous magnetorheological elastomers
Archive of Applied Mechanics, May 2023 This is a preview of a remote PDF: https://link.springer.com/content/pdf/10.1007/s00419-023-02437-w.pdf Eraslan, Sinan, Gitman, Inna, Askes, Harm, de Borst, René. , Archive of Applied Mechanics, 2023, pp. 1-15, DOI: 10.1007/s00419-023-02437-w
An automatic entropy method to efficiently mask histology whole-slide images
Scientific Reports, Apr 2023 This is a preview of a remote PDF: https://www.nature.com/articles/s41598-023-29638-1.pdf Song, Yipei, Cisternino, Francesco, Mekke, Joost M., de Borst, Gert J., de Kleijn, Dominique P. V., Pasterkamp, Gerard, Vink, Aryan, Glastonbury, Craig A., van der Laan, Sander W., Miller, Clint L.. , Scientific Reports, DOI: 10.1038/s41598-023-29638-1
Comparison of cardiovascular biomarker expression in extracellular vesicles, plasma and carotid plaque for the prediction of MACE in CEA patients
Scientific Reports, Feb 2023 This is a preview of a remote PDF: https://www.nature.com/articles/s41598-023-27916-6.pdf Verwer, Maarten C., Mekke, Joost, Timmerman, Nathalie, Waissi, Farahnaz, Boltjes, Arjan, Pasterkamp, Gerard, de Borst, Gert J., de Kleijn, Dominique P. V.. , Scientific Reports, DOI: 10.1038/s41598-023-27916-6
Themenheft Regenwasser-Management 2023 erschienen
24. März 2023 Themenheft Regenwasser-Management 2023 erschienen Titelbild BIRCOprime®: Erstklassige Sedimentation auf ganzer Linie - Die BIRCOprime® mit einer Länge von 4.500 mm, sorgt bei Starkregen für eine zuverlässige Linienentwässerung. Dieses System kann jedoch so viel mehr! Die neue Regenwasserbehandlungsanlage BIRCOprime® reinigt das abzuleitende Wasser noch während des Abfließens. Dieser Prozess geschieht unsichtbar direkt in einem Teil der Entwässerungsanlage.
A Bidirectional Mendelian Randomization Study to evaluate the causal role of reduced blood vitamin D levels with type 2 diabetes risk in South Asians and Europeans | Nutrition Journal | Full Text
Cynthia A. Bejar1, Shiwali Goyal1, Shoaib Afzal2,3,4, Massimo Mangino5,6, Ang Zhou7, Peter J. van der Most8, Yanchun Bao9, Vipin Gupta10, Melissa C. Smart9, Gagandeep K. Walia11, Niek Verweij12, Christine Power13, Dorairaj Prabhakaran11, Jai Rup Singh14, Narinder K. Mehra15, Gurpreet S. Wander16, Sarju Ralhan16, Sanjay Kinra17, Meena Kumari9, Martin H. de Borst12, Elina Hyppönen7,13,18, Tim D. Spector5, 2,3,4, Piers R.
Smoking is Associated to DNA Methylation in Atherosclerotic Carotid Lesions
Siemelink, MA; van der Laan, SW; Haitjema, S; van Koeverden, ID; Schaap, J; Wesseling, M; de Jager, SCA; ...
Mediterranean style diet is associated with low risk of new-onset diabetes after renal transplantation
The prevalence of patients with end-stage renal disease for which patients require chronic dialysis or renal transplantation, also called renal replacement therapy, is increasing at a rate of 7% per year.1 Renal transplantation improves quality of life and increases survival, compared to dialysis treatment.2 ,3 However, the results are not impressive, since a lot of factors impair survival after renal transplantation.
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