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de las Heras Alonso

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Articles

Familial melanoma: genetic, clinical, and dermoscopic insights and follow-up

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By Riga Stradinš, Alise Emma, de las Heras Alonso
| Frontiers
Abstract Familial melanoma accounts for approximately 5–10% of all melanoma cases. It is characterized by an earlier age of onset. Multiple primary melanomas occur in up to a fifth of patients with a positive family history, compared to 5% in sporadic cases. Pathologically, familial melanomas tend to present at thinner Breslow depths and show a higher proportion of in situ lesions compared to their sporadic counterparts, with a predilection for the lower limbs.
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