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Articles

Multiparametric senescence profiling by spectral flow cytometry uncovers endothelial heterogeneity following irradiation

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By Mohamed Amine, Autorité de Sûreté Nucléaire, de Radioprotection
| TechTrends
Cellular senescence can be premature in response to high levels of ROS, oncogene activation or radiation. Although radiation is now well known to induce this state of senescence, there appears to be considerable heterogeneity in the response among surviving cells. This is particularly true for endothelial cells, whose dysfunction is the basis for many radiation related complications.
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Presymptomatic microRNA-based biomarker signatures for the prognosis of localized radiation injury in mice

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By Lucie Ancel, de Radioprotection, Jules Gueguen, Guillaume Thoër
| PLOS ONE
Loading metrics Open Access Peer-reviewed Research Article Citation: Ancel L, Gueguen J, Thoër G, Marçais J, Chemloul A, Le Guen B, et al. (2025) Presymptomatic microRNA-based biomarker signatures for the prognosis of localized radiation injury in mice. PLoS One 20(8): e0329737. https://doi.org/10.1371/journal.pone.0329737 Editor: Daniel X. Zhang, Hong Kong Metropolitan University, HONG KONG Received: May 15, 2025; Accepted: July 20, 2025; Published: August 8, 2025 Copyright: © 2025 Ancel et al.
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