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Decoding Sequence-Structure-Function-Evolution of basic Leucine Zippers of Aureochromes from Heterokont Algae
Abstract The blue light photoreceptor cum transcription factors, Aureochromes (Aureos), are present exclusively in photosynthetic stramenopiles. Co-existence of Light Oxygen Voltage (LOV) and basic leucine zipper (bZIP) is unique to Aureos and therefore ideal to study light-dependent DNA binding or, transcriptional regulation. Further, the inverse effector-sensor topology of Aureos, resembling several sensory eukaryotic transcription factors, makes them prototypical optogenetic scaffolds.
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