Debashis Barik
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Three-site cycloadditions within one reaction intermediate with site-selectivity controlled by electronic and size bias
Abstract In homogeneous catalysis, a reaction intermediate typically possesses only one reactive site to ensure chemoselectivity. However, such a design limits efficiency and requires multiple independent steps to achieve divergent synthesis. What if a single intermediate could act as a “master key” featuring multiple, differentiated sites that each respond selectively to distinct partners?
Bioactive fungal compounds as potential anti-HIV agents against HIV-1 protease: a multi-faceted molecular modelling approach for drug discovery
Abstract HIV-PR is a prominent pharmacological target that is driving the development of various possible HIV inhibitors. Unfortunately, the viral strain population has evolved to be even more resistant to medications; therefore, studying the dynamic structures of both WT and mutant viruses, besides their interactions with inhibitors, may be advantageous.
Two Distinct Diazo-Diazo Cross-Coupling Reactions between α-Aryldiazo Ketones and Vinyldiazo Esters Using Gold Catalyst and Tetrabutylammonium Fluoride | Organic Letters
Organic Letters Cite this: Org. Lett. 2025, XXXX, XXX Click to copy citationCitation copied! . This publication is licensed under CC-BY 4.0 . You are free to share (copy and redistribute) this article in any medium or format and to adapt (remix, transform, and build upon) the material for any purpose, even commercially within the parameters below: Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator.
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