Debora Baroni

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All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.

1. Introduction Cystic fibrosis (CF) is an autosomal recessive disease caused by variants in the cystic fibrosis transmembrane conductance regulator (CFTR) protein, a chloride and bicarbonate channel located on the apical side of epithelia, where it plays a critical role in maintaining the electrolyte and fluid balance of the surface liquid layer [1,2]. The lack or dysfunction of CFTR results in thick secretions that cause gastrointestinal, reproductive, and respiratory system defects.