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Abstract Alpha-1 antitrypsin (AAT) is a serine protease inhibitor that protects tissue from neutrophil elastase and other proteases, particularly in the lung. Mutations in SERPINA1, including the Z mutation, lead to AAT deficiency (AATD), characterized by reduced circulating AAT and increased risk of pulmonary emphysema, liver cirrhosis, and hepatocellular carcinoma.
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INVITED EDITORIAL PDF ShareShare Abstract LINKED CONTENT This article is linked to Rocco et al and Celsa & Cammà papers. To view these articles, visit https://doi.org/10.1111/apt.16239 and https://doi.org/10.1111/apt.16250 To the Editor: We thank Drs.
ORIGINAL ARTICLE Alba Rocco Corresponding Author a.rocco@unina.it Department of Clinical Medicine and Surgery, Gastroenterology, University Federico II, Naples, Italy Correspondence Gerardo Nardone and Alba Rocco, Department of Clinical Medicine and Surgery, Gastroenterology Unit, University "Federico II", Via S. Pansini n° 5, 80131 Naples, Italy. Emails: nardone@unina.it (G. N.) and a.rocco@unina.it (A.
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