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Debora Inacio Leite

As seen in: MDPI
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Articles

Antiplasmodial, Trypanocidal, and Genotoxicity In Vitro Assessment of New Hybrid α,α-Difluorophenylacetamide-statin Derivatives

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By Debora Inacio Leite, Carlos Fernando Araujo-Lima, Sandra Loureiro Rosario, Kelly Salomão
| MDPI
Open AccessArticle by Carlos Fernando Araujo-Lima 1,2,3, Rita de Cassia Castro Carvalho 4,5, Sandra Loureiro Rosario 4, Debora Inacio Leite 4,6, Anna Caroline Campos Aguiar 7, Lizandra Vitoria de Souza Santos 2, Julianna Siciliano de Araujo 1, Kelly Salomão 1, Carlos Roland Kaiser 5, Antoniana Ursine Krettli 7, Monica Macedo Bastos 4, Claudia Alessandra Fortes Aiub 3, Maria de Nazaré Correia Soeiro 1,*, Nubia Boechat 4,* and Israel Felzenszwalb 2,* 1 Laboratório de Biologia Celular, LBC...
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A Review of the Development of Multitarget Molecules against HIV-TB Coinfection Pathogens

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By Debora Inacio Leite, Monica Macedo Bastos, Gustavo Peixoto Machado
| MDPI
1.4. Multitargets A single molecule that can interact with two or more distinct targets is defined as a multitarget. Multitargets are a novel concept in drug development that may provide a modern approach to the treatment of multifactorial diseases or diseases for which treatment is based on drug cocktails [59,60,61,62]. Such compounds have synergistic interactions with different bioreceptors and could thus be considered safer and more effective than conventional drugs [63,64].
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The Use of Zidovudine Pharmacophore in Multi-Target-Directed Ligands for AIDS Therapy

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By Nubia Boechat, Maria Laura Bolognesi, Debora Inacio Leite, Elisa Uliassi
| MDPI
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
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