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Débora Marques de Miranda on Muck Rack

Débora Marques de Miranda

As seen in: Nature
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Articles

Diagnostic performance of plasma pTau217 in genetically admixed South American populations

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By Pamela V. Martino-Adami, Hanna Huber, Julio Fernandez, Julio Fernández, María Bárbara Postillone, Natalia Silva Verified, Natália Silva, Andrea Carvalho, Mariana N. Vallejo-Azar, Stefanie Heilmann-Heimbach, Silvia Kochen, Patricia Solis, Anja Schneider, Paula Gonzalez, Paula González, Maria Carolina Dalmasso, Alfredo M. Ramirez, Alfredo Ramírez, Joice Coutinho de Alvarenga, Pilar Freccero, Ines Mintz, Nancy Medel, Erika de Oliveira Hansen, Julieta Lisso, Nicolás Irureta, Débora Marques de Miranda, Jonas Jardim de Paula, Rafaela Teixeira de Ávila, Bernardo de Mattos Viana
| Nature Verified
Abstract Plasma pTau217 is a leading biomarker for Alzheimer’s disease, but evidence from genetically admixed populations in low- and middle-income countries remains limited. We evaluated the diagnostic performance of pTau217 and pTau217/Aβ42 measured using Simoa technology in memory-clinic cohorts from Brazil (Cog-Aging-Study, n = 353) and Argentina (GeNED.ar, n = 134).
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