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Coordinated interplay between palmitoylation, phosphorylation and SUMOylation regulates kainate receptor surface expression
Introduction Kainate receptors (KARs) are ionotropic glutamate receptors distributed throughout the brain at pre-, post-, and extrasynaptic sites, depending on the neuronal subtype and synapse in question.
Modulator-Gated, SUMOylation-Mediated, Activity-Dependent Regulation of Ionic Current Densities Contributes to Short-Term Activity Homeostasis
Research Articles, Cellular/Molecular Anna R. Parker, Lori A. Forster and Deborah J. Baro Journal of Neuroscience 23 January 2019, 39 (4) 596-611; DOI: https://doi.org/10.1523/JNEUROSCI.1379-18.2018 Abstract Neurons operate within defined activity limits, and feedback control mechanisms dynamically tune ionic currents to maintain this optimal range.
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