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Deike J. Omnus on Muck Rack

Deike J. Omnus

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Articles

The heat shock protein LarA activates the Lon protease in response to proteotoxic stress - Nature Communications

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By Deike J. Omnus, Matthias Fink, Axel Leppert, Michael Landreh, Aswathy Kallazhi
| Nature Verified
Abstract The Lon protease is a highly conserved protein degradation machine that has critical regulatory and protein quality control functions in cells from the three domains of life. Here, we report the discovery of a α-proteobacterial heat shock protein, LarA, that functions as a dedicated Lon regulator.
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A heat-sensitive Osh protein controls PI4P polarity

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By Ffion Thomas, Christopher J. Stefan, Deike J. Omnus, Angela Cadou
| Biomed Central (BMC)
Abstract Background Phosphoinositide lipids provide spatial landmarks during polarized cell growth and migration. Yet how phosphoinositide gradients are oriented in response to extracellular cues and environmental conditions is not well understood. Here, we elucidate an unexpected mode of phosphatidylinositol 4-phosphate (PI4P) regulation in the control of polarized secretion.
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