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Delna Irani on Muck Rack

Delna Irani

As seen in: Taylor & Francis Online
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Articles

Higher sperm H3K4me3 levels are associated with idiopathic recurrent pregnancy loss

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By Vandana Bansal, Delna Irani, Deepshikha Arya, Deepti Tandon
| Taylor & Francis Online
ABSTRACT During fertilization, spermatozoa contribute genetic and epigenetic factors such as chromatin packaged with protamines and histones; DNA methylome, non-coding RNAs, etc. Human sperm chromatin retains 5–15% nucleosomes which can play a key role in embryonic development. Recurrent pregnancy loss (RPL) is a condition mainly attributed to defects in embryo and placenta development.
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