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Articles by Denis Gris
Use of animal models to understand CNS neuroimmunology — guidance from the International Society for Neuroimmunology White Paper Task Force
Abstract Neuroimmunology is a rapidly expanding field in which many breakthroughs have been fuelled by studies in animal models that capture aspects of human neurological disease. However, the variety of animal models available, with their relative merits and drawbacks, is not well documented in the literature, posing a hurdle for scientists who are venturing into the world of neuroimmunology.
Oxidative stress in Wernicke’s encephalopathy
Jun-Dong Wei1 * and Xueming Xu2 * 1Department of Basic Medical Science, Medical College, Taizhou University, Taizhou, China 2Department of Psychiatry, Taizhou Second People’s Hospital, Taizhou, China Wernicke’s encephalopathy (WE) is a severe life-threatening disease that occurs due to vitamin B1 (thiamine) deficiency (TD). It is characterized by acute mental disorder, ataxia, and ophthalmoplegia.
Multi-view image-based behavior classification of wet-dog shake in Kainate rat model
1. Introduction Animal behavior analysis plays an essential role in pre-clinical models investigating the causes of human diseases. Hence, automating and finding new insights into behaviors is fundamental to accelerating research. Machine vision techniques are widely recognized as effective instruments for automating behavior analysis. However, most systems are limited to one view, in mice, usually from the top. Nevertheless, a single view cannot be used to detect all behaviors.
Automated Grooming Detection of Mouse by Three-Dimensional Convolutional Neural Network
Introduction Experimental animals exhibit various behaviors, such as ambulation, immobility, rearing, scratching, and grooming. Since behavior reflects the mental and physical condition of an animal, we can estimate it by observing its behavior. Grooming is one of the common behaviors to care for fur, maintain hygiene, and regulate body temperature in experimental animals such as mice, rats, and others (Almeida et al., 2015; Kalueff et al., 2016).
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