Denisse A. Castro

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Background: Globally, acral melanoma (AM) is underrepresented in most clinical trials, being predominant in Caucasian populations. Latin America is a niche that needs to be explored. Therefore, this study aimed to determine the clinical features, response patterns, outcomes and v-raf murine sarcoma viral oncogene homolog B1 (BRAF) status in Peruvian patients with advanced AM.

Adult T-cell leukemia/lymphoma (ATLL) is a mature, peripheral T-cell neoplasm caused by the human T-cell leukemia virus type 1 (HTLV-1).1,2 HTLV-1 infects up to 10 million people worldwide and it is predominantly transmitted via breastfeeding, blood transfusion, sharing of needles, and sexual intercourse.3 The virus is endemic in southwestern Japan, the Caribbean Basin, South America, Western and Central Africa, and central Australia.3,4 In Latin America, the highest prevalence is found in...