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Deniz C Guven on Muck Rack

Deniz C Guven

As seen in: Nature, Future Medicine
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Articles

Biallelic SLC20A2 loss-of-function in severe early-onset neurodevelopmental disorder with brain calcification

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By Mehmet Burak Mutlu, Abdullah Sezer, Elif Ozdemir, Ayse Kacar Bayram, Deniz C Guven, Şükriye Yılmaz, Deniz Karatas, Özlem Öz, Nil Sazlı, Emine Öz, Zeynep Bayramlar
| Nature Verified
Abstract Biallelic SLC20A2 variants have recently been linked to a severe childhood-onset phenotype distinct from classical adult-onset primary brain calcification, but the molecular and radiologic consequences of homozygous truncating variants remain incompletely defined. We describe a child with severe early-onset neurodevelopmental disease caused by a homozygous SLC20A2 nonsense variant and provide clinical, neuroradiologic, segregation, and transcript-level characterization.
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AI-supported chatbots as triggers of potential communication crises: a phenomenological study of user experiences

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By Murat Seyfi, Hıdır Polat, Deniz C Guven, Yeliz Kuşay
| Nature Verified
Abstract Artificial intelligence (AI)-supported chatbots have become a common communication interface between organizations and their stakeholders. Although these systems are designed to enhance efficiency and accessibility, failures in chatbot interactions may generate unexpected communication tensions at the user level. This study examines how chatbot interaction failures may evolve into micro-level communication crises from the user experience perspective.
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KELIM score predicts outcome in patients with platinum-resistant/refractory recurrent ovarian cancer

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By Deniz C Guven, Hasan YILDIRIM, Elvin Chalabiyev, Fatih Kus
| Future Medicine Verified
Biomarkers in MedicineAhead of Print Research Article Published Online: Abstract Aim: To assess the prognostic role of the CA-125 elimination rate constant K (KELIM) score in platinum-resistant/refractory ovarian cancer patients receiving second-line treatment. Methods: A retrospective study was carried out including 117 patients with advanced-stage platinum-resistant/refractory ovarian cancer treated with liposomal doxorubicin ± bevacizumab.
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