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Deren Birol on Muck Rack

Deren Birol

As seen in: BioRxiv
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Articles

The presenting HLA determines fidelity of SARS-CoV-2 spike protein epitope prediction

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By Charles Schutt, Xiuyuan Lu, Sho Yamasaki, Deren Birol
| BioRxiv
Abstract During the course of the COVID-19 pandemic, multiple studies used prediction methods to identify potential epitopes. While additional studies identified epitopes from convalescent and vaccinated subjects, few studies have compared the predicted to identified epitopes. Here we used three methods alone and in combination to predict helper T cell epitopes and compared the results to experimentally determined peptide binding.
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