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Devanash Tandon on Muck Rack

Devanash Tandon

As seen in: BioRxiv
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Articles

How clinically relevant are prostate cancer cell lines? A comprehensive characterisation and multiomics comparison.

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By Zahra Ahmed, Umber Cheema, Warda Mosabbir, Devanash Tandon
| BioRxiv
Abstract Cell line experiments arguably remain the most used tool in preclinical cancer research, despite their limitations. With almost 95% drugs entering human trials failing, and up to 90% preclinical research failing before even being tested in humans, we must shift the pre-clinical paradigm. A range of in silico, in vitro, in vivo and ex vivo approaches are gaining popularity, with the aim of potentially replacing cell line use.
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