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Dewa Kresna on Muck Rack

Dewa Kresna

As seen in: BioRxiv
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Articles

Nanoliter-scale selection of optimized bioengineered peptide antibiotics that rescue mice with bacterial lung infection

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By Michael Marner, Nils Boehringer, Zerlina G Wuisan, Dewa Kresna
| BioRxiv
Abstract Increasing numbers of multi-drug resistant pathogens call for new chemical scaffolds, addressing novel targets, that can serve as lead structures for the development of life-saving drugs. For antibiotics, natural product-inspired molecules represent a most promising resource. Natural products evolved to high chemical complexity and occupy a chemical space different than synthetic libraries.
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