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Dharmender K. Gahlot on Muck Rack

Dharmender K. Gahlot

As seen in: Nature, MDPI
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Articles

Cpx-signalling in Yersinia pseudotuberculosis modulates Lipid-A remodelling and resistance to last-resort antimicrobials - npj Antimicrobials and Resistance

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By Dharmender K. Gahlot, Luke P. Allsopp, Alain Filloux, Matthew Francis
| Nature Verified
Abstract Antibiotic resistance is a global healthcare crisis. Bacteria are highly adaptable and can rapidly acquire mechanisms of resistance towards conventional antibiotics. The permeability barrier conferred by the Gram-negative bacteria cell envelope constitutes a first line of defence against the action of antibiotics.
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The F-pilus biomechanical adaptability accelerates conjugative dissemination of antimicrobial resistance and biofilm formation - Nature Communications

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By Jonasz B. Patkowski, Himani Amin, Dharmender K. Gahlot, Joseph Vogel, Matthew Francis, Joseph Baker, Magnus Andersson
| Nature Verified
Abstract Conjugation is used by bacteria to propagate antimicrobial resistance (AMR) in the environment. Central to this process are widespread conjugative F-pili that establish the connection between donor and recipient cells, thereby facilitating the spread of IncF plasmids among enteropathogenic bacteria. Here, we show that the F-pilus is highly flexible but robust at the same time, properties that increase its resistance to thermochemical and mechanical stresses.
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Diversity in Genetic Regulation of Bacterial Fimbriae Assembled by the Chaperone Usher Pathway

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By Sheila MacIntyre, Dharmender K. Gahlot, Nayyer Taheri
| MDPI
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