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Di Yin

As seen in: Nature, Wiley Online Library, arXiv, Diario AS, PLOS ONE, Frontiers in Immunology, MDPI, Flipboard, Science Magazine, Royal Society of Chemistry and
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Articles

A generalizable covalent car-t platform for solid tumors enabled by oncolytic adenovirus-delivered artificial antigens

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By Hui Xie, Di Yin, Guidong Zhu, Guojing Pei, Wen Zhang, Fang Xiao, Dongqi Tang, Linpei Guo, Peichao Zhai, Jiaju Lyu
| Frontiers in Immunology
Abstract Background: Chimeric antigen receptor (CAR) T-cell therapy has shown limited efficacy against solid tumors due to antigen heterogeneity and scarcity of tumor-specific targets. Methods: To address those challenges, we report a covalent CAR-T strategy that achieves programmable tumor recognition via oncolytic adenovirus-mediated (OAD) delivery of artificial antigens.
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Autonomous biomedical research with an artificial intelligence agent

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By J. C. Brüggenjürgen, Gerard Crowley, Zhulatai Bao, Kexin Huang, serena zhang, Hanchen Wang, Yuanhao Qu, Yingzhou Lu, Ryan Li, Yusuf Roohani, Lin Qiu, Shiyi Cao, Gavin Li, Junze Zhang, Di Yin, Rick Wierenga, Deniz Kavi, Sherry Liu, Shruti Marwaha, Jennefer N. Carter, Xin Zhou, Matthew Wheeler, Jonathan Bernstein, Mengdi Wang, Peng He
| Science Magazine Verified
Abstract Supplementary Materials References and Notes Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Abstract Biomedical research is increasingly constrained by repetitive, fragmented workflows that slow discovery. We introduce Biomni, a general-purpose biomedical artificial intelligence agent that autonomously executes diverse research tasks.
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Futbolistas españoles que eligieron jugar con otra selección

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By Di Yin, Laurence Griffiths, Eddie Keogh
| Diario AS Verified
Rodrigo Zalazar, UruguayFOTO: NurPhoto / NurPhoto via Getty Images Nació en Albacete, pero su historia futbolística tiene otro destino. Hijo del exjugador uruguayo José Luis Zalazar, creció entre España y el legado de su familia, con doble nacionalidad desde pequeño. Aunque se formó en el fútbol español y dio el salto a Europa, siempre tuvo otra opción sobre la mesa. Finalmente eligió representar a Uruguay, el país de sus raíces, con el que debutó en 2023.
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