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Diarra Oden

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Articles

The lateral habenula is required for maternal behavior in the mouse dam

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By Jessie Benedict, Robert H. Cudmore, David Linden, Diarra Oden
| BioRxiv
Abstract Mammalian parenting is an unusually demanding commitment. How did evolution co-opt the reward system to ensure parental care? Previous work has implicated the lateral habenula (LHb), an epithalamic nucleus, as a potential intersection of parenting behavior and reward. Here, we examine the role of the LHb in the maternal behavior of naturally parturient mouse dams. We show that kainic acid lesions of the LHb induced a severe maternal neglect phenotype in dams towards their biological pups.
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