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Diego Jose Belato on Muck Rack

Diego Jose Belato

As seen in: Frontiers in Immunology
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Articles

Bacillus Calmette-Guérin as adjuvant platform enhances immunogenicity of conserved epitopes from structural proteins of SARS-CoV-2

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By Ana de Souza, de Araujo, Diego Jose Belato
| Frontiers in Immunology
Abstract The development of effective and broadly protective vaccines against SARS-CoV-2 remains a global priority. Conserved epitopes from viral structural proteins (E, M, N, and S) represent promising targets less affected by emerging mutations, while Bacillus Calmette-Guérin (BCG) offers unique adjuvant and delivery properties. This study aimed to validate conserved SARS-CoV-2 epitopes in combination with BCG and to design multiepitope vaccine constructs in silico.
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