Dieval Guizelini on Muck Rack

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a2iHelper: a Python toolkit for a differential editing site analysis of RNA-Seq data

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By Guilherme Ribas, Leonardo V. Riella, Cristian Riella, Dieval Guizelini
| biorxiv.org
Abstract A-to-I RNA editing, mediated by ADAR enzymes, plays a crucial role in cancer and autoimmune disorders but lacks standardized tools for differential analysis. After reviewing 55 studies, it highlights significant methodological heterogeneity, hindering result comparability and reproducibility. To address this, we developed a2iHelper, a Python package that streamlines RNA editing analysis by filtering noise, performing statistical analyses, and generating visualizations.
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