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Digdem Yoyen-Ermis on Muck Rack

Digdem Yoyen-Ermis

As seen in: AIChE Journal, Color Research & Application, PLOS ONE
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Articles

Pro-fibrogenic and adipogenic aspects of chronic muscle degeneration are contributed by distinct stromal cell subpopulations

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By Cansu Özdemir, Duygu AkÇay, Digdem Yoyen-Ermis, Ekim Zihni Taşkıran
| PLOS ONE
Loading metrics Open Access Peer-reviewed Research Article Abstract Chronic skeletal muscle degeneration is characterized by fiber atrophy accompanied by deposition of extracellular matrix (ECM) components and fatty infiltration. Excessive accumulation of ECM leads to fibrosis via the contribution of fibro-adipogenic precursors (FAPs). Fibrosis also accompanies disuse atrophy and sarcopenia without significant inflammation.
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By Digdem Yoyen-Ermis, Didem Ozkazanc, Mustafa Gurbuz, Gunes Esendagli, Kivilcim Ozturk-Atar, M. Alper Kursunel, Cisel Aydin, Aysegul Uner, Metin Tulu, Sema Calis
| American Chemical Society
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Functional exhaustion of CD4+ T cells induced by costimulatory signals from myeloid leukemia cells

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By Didem Ozkazanc, Digdem Yoyen-Ermis, Ece Tavukcuoglu, Yahya Buyukasik, Gunes Esendagli
| AIChE Journal Verified
To cope with immune responses, tumor cells implement elaborate strategies such as adaptive resistance and induction of T cell exhaustion. T cell exhaustion has been identified as a state of hyporesponsiveness that arises under continuous antigenic stimulus. Nevertheless, contribution of costimulatory molecules to T cell exhaustion in cancer remains to be better defined.
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