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Dinku Yigezaw

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Articles

Host STING signaling is associated with gut microbiota, bile acid metabolism, and mucosal immune defense during Salmonella infection

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By Anhui Agricultural, Dinku Yigezaw
| TechTrends
Background The gut microbiota and its metabolites are important regulators of mucosal immunity against enteric pathogens. However, the host pathways that coordinate intestinal microbial ecology, bile acid metabolism, and antibacterial defense remain incompletely understood. STING is a key adaptor in nucleic acid sensing, but its role in shaping the intestinal microbial-metabolic environment during bacterial infection is unclear.
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