Diptiben Parekh on Muck Rack

Diptiben Parekh

As seen in: Science Magazine, BioRxiv
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Articles

Intracellular Ebola Virus nucleocapsid assembly revealed by in situ cryo-electron tomography.

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By Reika Watanabe, Dawid Zyla, Diptiben Parekh, Connor Hong
| BioRxiv
Abstract Filoviruses, including Ebola and Marburg viruses, are a family of highly lethal viruses that cause severe hemorrhagic fever in humans with near annual outbreaks. Antiviral options are limited, and broad-spectrum antivirals are needed. The core of the filamentous virion is formed by the nucleocapsid, a helical structure in which the polymerized nucleoprotein (NP) assembles on the RNA genome and is surrounded by viral proteins VP24 and VP351,2.
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