Dirk-Bart den Ouden

Abstract Sharing neuroimaging datasets enables reproducibility, education, tool development, and new discoveries. Neuroimaging from many studies are publicly available, providing a glimpse into progressive disorders and human development. In contrast, few stroke studies are shared, and these datasets lack longitudinal sampling of functional imaging, diffusion imaging, as well as the behavioral and demographic data that encourage novel applications.

Abstract The classical assumption that Wernicke’s area supports word and sentence comprehension has been questioned following discrepant results in primary progressive aphasia. We tested the hypothesis of Mesulam et al. (2015; 2019) that word and sentence comprehension deficits in stroke-based aphasia result from ‘double disconnection’ of both anterior temporal lobe and inferior frontal lobe to temporoparietal cortex due to white matter damage, rather than dysfunction of Wernicke’s area itself.