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Divyanshu Sahu

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Articles

The deSUMOylase SPF2 and the cohesin regulators SGO2 and CTF18 suppress crossovers near centromeres

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By Joiselle Blanche Fernandes, Qichao Lian, DipEsh SinGh, Stéphanie Durand, Hernan Lopez, Raphael Mercier, Rigel Salinas Gamboa, Divyanshu Sahu, Laia Capilla-Perez, Alexandra Kalde
| Nature Verified
Abstract Crossovers (COs) ensure proper chromosome segregation during meiosis and generate genetic diversity. COs are non-uniformly distributed along chromosomes and almost universally suppressed in centromere-proximal regions, notably creating an important bottleneck for plant breeding. The mechanism of this CO suppression is still not fully understood, but the chromatin state is a contributing factor.
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