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Donald Stephen Serafin on Muck Rack

Donald Stephen Serafin

As seen in: BioRxiv
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Articles

Lymphatic activation of ACKR3 signaling regulates lymphatic response after ischemic heart injury.

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By Laszlo Balint, Shubhangi Patel, Hua Zhang, Donald Stephen Serafin
| BioRxiv
Abstract Background: Ischemic heart disease is a prevalent cause of death and disability worldwide. Recent studies reported a rapid expansion of the cardiac lymphatic network upon ischemic heart injury and proposed that cardiac lymphatics may attenuate tissue edema and inflammatory mechanisms after ischemic heart injury. Nevertheless, the mechanisms through which hypoxic conditions affect cardiac lymphangiogenesis and function remain unclear.
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