Donald Weaver
As seen in:
Yahoo Life,
Nature,
Yahoo Canada,
The Conversation,
Flipboard,
CNA (Channel NewsAsia),
The Epoch Times,
Rappler,
Medical Xpress,
Diario Sur
and
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Donald Weaver
The future of surgery
Abstract Surgery is entering a period of accelerated transformation driven by artificial intelligence, robotics, and emerging postmodern medical technologies. Unlike prior technological shifts, innovation cycles are compressing into years, challenging established models of evidence generation, regulation, training, and professional identity.
5 façons de prévenir la maladie d'Alzheimer et la démence
Donald Weaver est professeur de chimie et chercheur principal au Krembil Research Institute de l'Université de Toronto et Emma Twiss est étudiante de premier cycle en sciences de la vie à l'Université Queen's. La maladie d'Alzheimer (MA) est sur le point de devenir un des principaux défis de santé publique de notre temps. Toutes les trois secondes, une personne est diagnostiquée avec une démence, le plus souvent la maladie d'Alzheimer, quelque part dans le monde.
SHIELD: A simple, Memorable Model to Help Prevent Alzheimer’s Disease and Dementia
Alzheimer’s disease (AD) is on track to become one of the defining public health challenges of our time. Every three seconds, somewhere in the world, someone is diagnosed with dementia, and it’s usually Alzheimer’s disease. Currently, approximately 50 million people worldwide have AD. By 2050, this number will exceed 130 million. The human health and socioeconomic consequences of this are going to be immense. But perhaps it doesn’t have to be this way.
SHIELD : prévenir la maladie d’Alzheimer et la démence grâce à un modèle simple et facile à retenir
La maladie d’Alzheimer (MA) est sur le point de devenir un des principaux défis de santé publique de notre temps. Toutes les trois secondes, une personne est diagnostiquée avec une démence, le plus souvent la maladie d’Alzheimer, quelque part dans le monde. Actuellement, environ 50 millions de personnes souffrent de la maladie d’Alzheimer. D’ici 2050, ce chiffre pourrait dépasser les 130 millions. Cet article fait partie de notre série La Révolution grise.
SHIELD: A simple, memorable model to help prevent Alzheimer’s disease and dementia
Alzheimer’s disease (AD) is on track to become one of the defining public health challenges of our time. Every three seconds, somewhere in the world, someone is diagnosed with dementia, and it’s usually Alzheimer’s disease (AD). Currently, approximately 50 million people worldwide have AD. By 2050, this number will exceed 130 million. The human health and socioeconomic consequences of this are going to be immense. But perhaps it doesn’t have to be this way.
SHIELD: A simple, memorable model to help prevent Alzheimer’s disease and dementia Original
Alzheimer’s disease (AD) is on track to become one of the defining public health challenges of our time. Every three seconds, somewhere in the world, someone is diagnosed with dementia, and it’s usually Alzheimer’s disease. Currently, approximately 50 million people worldwide have AD. By 2050, this number will exceed 130 million. The human health and socioeconomic consequences of this are going to be immense. But perhaps it doesn’t have to be this way.
It’s unlikely a magic bullet will ever cure Alzheimer’s - maybe a magic shotgun can
For much of the 21st century, one theory has dominated research efforts to cure Alzheimer’s disease: the amyloid hypothesis. Beta-amyloid is a protein that builds up in clumps, or plaques, in the brains of people with Alzheimer’s disease and is linked to their cognitive decline. But in recent years, despite the emergence of a couple of new drugs targeting these plaques, some scientists have begun to doubt the amyloid hypothesis.
New theories of Alzheimer’s taking the search for a cure in a different direction - podcast
For much of the 21st century, one theory has dominated research efforts to cure Alzheimer’s disease: the amyloid hypothesis. Beta-amyloid is a protein that builds up in clumps, or plaques, in the brains of people with Alzheimer’s disease and is linked to their cognitive decline. But in recent years, despite the emergence of a couple of new drugs targeting these plaques, some scientists have begun to doubt the amyloid hypothesis.
Should AD stand for Alzheimer's disease, or for Auguste Deter, the patient whose case was first described?
Auguste Deter was born 175 years ago on May 16, 1850. Though the story of her life is not widely known, it should be. Through her suffering and dignity, Deter puts a much-needed human face on the tragedy of Alzheimer's disease (AD), one of the most important medical problems currently confronting humankind. Auguste Deter reminds us that AD is a disease of people, not proteins. Often, scientists reduce AD to a disorder of shrunken brain cells or misfolded proteins. However, AD is so much more.
Should AD stand for Alzheimer’s disease, or for Auguste Deter, the patient whose case was first described?
Auguste Deter was born 175 years ago on May 16, 1850. Though the story of her life is not widely known, it should be. Through her suffering and dignity, Deter puts a much-needed human face on the tragedy of Alzheimer’s disease (AD), one of the most important medical problems currently confronting humankind. Auguste Deter reminds us that AD is a disease of people, not proteins. Often, scientists reduce AD to a disorder of shrunken brain cells or misfolded proteins. However, AD is so much more.
Curing Alzheimer’s disease: Magic bullet or magic shotgun blast?
Why are researchers still fumbling in the quest to cure what is arguably one of the most important diseases confronting humankind — Alzheimer’s disease? Despite decades of research, there is still no curative treatment for Alzheimer’s – no “magic bullet” that stops this devastating degenerative brain disease in its tracks. Don't want to see this? Remove ads Not surprisingly, finding the magic bullet has become the holy grail for Alzheimer’s researchers. But it’s proving to be an immense challenge.
Curing Alzheimer's disease: Magic bullet or magic shotgun blast?
Why are researchers still fumbling in the quest to cure what is arguably one of the most important diseases confronting humankind—Alzheimer's disease? Despite decades of research, there is still no curative treatment for Alzheimer's—no "magic bullet" that stops this devastating degenerative brain disease in its tracks. Not surprisingly, finding the magic bullet has become the holy grail for Alzheimer's researchers. But it's proving to be an immense challenge.
Curing Alzheimer’s disease: Magic bullet or magic shotgun blast? Original
Why are researchers still fumbling in the quest to cure what is arguably one of the most important diseases confronting humankind — Alzheimer’s disease? Despite decades of research, there is still no curative treatment for Alzheimer’s – no “magic bullet” that stops this devastating degenerative brain disease in its tracks. Not surprisingly, finding the magic bullet has become the holy grail for Alzheimer’s researchers. But it’s proving to be an immense challenge.
Alzheimer's May Not Actually Be a Brain Disease, Expert Reveals
The pursuit of a cure for Alzheimer's disease is becoming an increasingly competitive and contentious quest with recent years witnessing several important controversies. In July 2022, Science magazine reported that a key 2006 research paper, published in the prestigious journal Nature, which identified a subtype of brain protein called beta-amyloid as the cause of Alzheimer's, may have been based on fabricated data.
Alzheimer's May Not Actually Be a Brain Disease, Expert Reveals
Eli Lilly has a lot going for it. Over the last couple of years, the pharmaceutical industry has been taken over by glucagon-like peptide-1 (GLP-1) …
Alzheimer's may be caused by immune cells thinking brain cells are bacteria, expert says
The pursuit of a cure for Alzheimer's disease is becoming an increasingly competitive and contentious quest with recent years witnessing several important controversies. In July 2022, Science magazine reported that a key 2006 research paper, published in the prestigious journal Nature, which identified a subtype of brain protein called beta-amyloid as the cause of Alzheimer's, may have been based on fabricated data.
Alzheimer's Might Not Actually Be a Brain Disease, Expert Reveals
By signing up for our newsletter, you agree to our Terms of Use and Privacy Policy
Alzheimer's Might Not Actually Be a Brain Disease, Expert Reveals
The pursuit of a cure for Alzheimer's disease is becoming an increasingly competitive and contentious quest with recent years witnessing several important controversies. In July 2022, Science magazine reported that a key 2006 research paper, published in the prestigious journal Nature, which identified a subtype of brain protein called beta-amyloid as the cause of Alzheimer's, may have been based on fabricated data.
Malnourishment masquerading as dementia
Adequate nutrition is crucial to cognition.
Teori baru tunjukkan bahwa Alzheimer bukan penyakit otak tapi penyakit autoimun
Pencarian obat untuk penyakit Alzheimer menjadi semakin kompetitif dan kontroversial. Beberapa tahun terakhir, pencarian ini melibatkan perdebatan seru. Pada Juli 2022, majalah Science melaporkan bahwa sebuah penelitian penting pada tahun 2006 dalam jurnal bergengsi Nature, yang mengidentifikasi subtipe protein otak yang disebut beta amiloid sebagai penyebab Alzheimer. Temuan ini mungkin didasarkan pada data palsu.
L’Alzheimer pourrait être une maladie auto-immune, et non pas une pathologie du cerveau
La recherche d’un traitement curatif de la maladie d’Alzheimer constitue une quête de plus en plus compétitive et litigieuse, ces dernières années ayant été marquées par plusieurs importantes controverses. En juillet 2022, le magazine Science a annoncé qu’un rapport de recherche de 2006, publié dans la prestigieuse revue Nature, qui identifiait un sous-type de protéine cérébrale appelé bêta-amyloïde comme la cause de la maladie d’Alzheimer, pourrait avoir reposé sur des données fabriquées.
Hay motivos para sospechar que el alzhéimer podría ser una enfermedad autoinmune
Encontrar una cura para la enfermedad de alzhéimer se está convirtiendo en un desafío cada vez más competitivo y polémico, y en los últimos años se han producido varias controversias importantes. Sin ir más lejos, en julio de 2022, la revista Science informó de que un trabajo de investigación clave de 2006 que identificaba un subtipo de proteína cerebral llamada beta-amiloide como la causa del alzhéimer podría haberse basado en datos inventados.
Alzheimer’s might not be primarily a brain disease. A new theory suggests it’s an autoimmune condition.
The pursuit of a cure for Alzheimer’s disease is becoming an increasingly competitive and contentious quest with recent years witnessing several important controversies. In July 2022, Science magazine reported that a key 2006 research paper, published in the prestigious journal Nature, which identified a subtype of brain protein called beta-amyloid as the cause of Alzheimer’s, may have been based on fabricated data.
SHIELD: A Simple, Memorable Model To Help Prevent Dementia
Up to one third of Alzheimer’s cases may be preventable. Neurologist Donald Weaver explains how SHIELD — Sleep, Head injury prevention, Exercise, Learning, Diet — turns complex risk science into simple steps to protect brain health. Alzheimer’s disease is on track to become one of the defining public health challenges of our time. Every three seconds, somewhere in the world, someone is diagnosed with dementia, and it’s usually Alzheimer’s disease.
Why Don't We Have A Cure For Alzheimer's Disease?
Currently, the only approved drugs for Alzheimer’s merely alleviate some of the symptoms — partially and temporarily — but do not stop the disease from progressing. (Shutterstock) As a researcher who studies Alzheimer’s disease and a neurologist who cares for people with Alzheimer’s, I share in the frustration, indeed anger, of people and families when I tell them that I have no cure to offer.
Why Don't We Have A Cure For Alzheimer's Disease?
Currently, the only approved drugs for Alzheimer’s merely alleviate some of the symptoms — partially and temporarily — but do not stop the disease from progressing. (Shutterstock) As a researcher who studies Alzheimer’s disease and a neurologist who cares for people with Alzheimer’s, I share in the frustration, indeed anger, of people and families when I tell them that I have no cure to offer.
¿Por qué aún no hay cura para el alzhéimer si se detectó hace más de 110 años?
Los únicos medicamentos aprobados para el alzhéimer solo alivian algunos de los síntomas, parcial y temporalmente, pero no detienen el progreso de la enfermedad. Como investigador del alzhéimer y neurólogo que atiende a personas con esta enfermedad, comparto la frustración —en realidad la ira— de las personas y las familias cuando les digo que no tengo una cura que ofrecerles.
Pourquoi n'y a-t-il toujours pas de traitements contre la maladie d'Alzheimer?
11h59 , le 23 mars 2021 Il n'y a toujours pas de traitement contre l'Alzheimer, connu officiellement depuis 115. Le cerveau humain est extrêmement complexe, et la maladie d'Alzheimer est sa maladie la plus complexe, explique Donald Weaver, professeur de chimie à l'université de Toronto.
Pourquoi n’y a-t-il toujours pas de traitement contre l’alzheimer ?
En tant que chercheur qui étudie la maladie d’Alzheimer et neurologue qui soigne des personnes qui en sont atteintes, je partage la frustration, voire la colère, des patients et des familles lorsque je leur dis que je n’ai aucun traitement à leur proposer. Au cours de la dernière année, les scientifiques se sont attaqués à la COVID-19, une maladie jusqu’alors inconnue, et ont mis au point en quelques mois de nouveaux vaccins efficaces contre le virus qui la cause.
Pourquoi n’avons-nous toujours pas de traitements contre l’Alzheimer?
Article réservé aux abonnés LA SCIENCE DANS SES MOTS / En tant que chercheur qui étudie la maladie d’Alzheimer et neurologue qui soigne des personnes atteintes de la maladie, je partage la frustration, voire la colère, des personnes et des familles lorsque je leur dis que je n’ai aucun traitement à leur proposer.
Why don’t we have a cure for Alzheimer’s disease?
Credit: CC0 Public Domain As a researcher who studies Alzheimer’s disease and a neurologist who cares for people with Alzheimer’s, I share in the frustration, indeed anger, of people and families when I tell them that I have no cure to offer. Over the past year, scientists have tackled COVID-19, a previously unknown disease and within months developed effective new vaccines. Over that same time frame, the list of Alzheimer’s treatment failures got longer.
Pourquoi n’avons-nous pas de traitements contre la maladie d’Alzheimer ?
En tant que chercheur qui étudie la maladie d’Alzheimer et neurologue qui soigne des personnes atteintes de la maladie, je partage la frustration, voire la colère, des personnes et des familles lorsque je leur dis que je n’ai aucun traitement à leur proposer. Au cours de la dernière année, les scientifiques se sont attaqués à la Covid-19, une maladie jusqu’alors inconnue, et ont mis au point en quelques mois de nouveaux vaccins efficaces contre le virus qui la cause.
Why don't we have a cure for Alzheimer's disease?
As a researcher who studies Alzheimer’s disease and a neurologist who cares for people with Alzheimer’s, I share in the frustration, indeed anger, of people and families when I tell them that I have no cure to offer. Over the past year, scientists have tackled COVID-19, a previously unknown disease and within months developed effective new vaccines. Over that same time frame, the list of Alzheimer’s treatment failures got longer.
Depression and Dementia in the Age of COVID-19: 2 Sides, 1 Coin
As social isolation takes hold, many older people face a greater risk of these closely linked conditions Every seven seconds, someone in the world is diagnosed with dementia. A typical case that I often see in my practice is as follows: A 76-year-old woman has a two-year history of progressive worsening of short-term memory and cognitive decline. She can’t recall the names of her grandchildren and is devastated by her deteriorating abilities.
Commentary: Depression and dementia during COVID-19 are two sides of a devastating coin
TORONTO: Every seven seconds, someone in the world is diagnosed with dementia. A typical case that I often see in my practice is as follows: A 76-year-old woman has a two-year history of progressive worsening of short-term memory and cognitive decline. Advertisement Advertisement She cannot recall the names of her grandchildren and is devastated by her deteriorating abilities. However, this is not the first time in her life that she has had feelings of loss and despair.
Depression and dementia in the age of COVID-19: Two sides, one coin
Every seven seconds, someone in the world is diagnosed with dementia. A typical case that I often see in my practice is as follows: A 76-year-old woman has a two-year history of progressive worsening of short-term memory and cognitive decline. She can’t recall the names of her grandchildren and is devastated by her deteriorating abilities. However, this is not the first time in her life that she has had feelings of loss and despair.
Depression and dementia in the age of COVID-19
More than half of patients with dementia also suffer from depression. If the depression remains untreated, the associated memory and cognitive problems worsen. Conversely, a significant history of depression seems to be a risk factor for dementia. Credit: Pixabay Every seven seconds, someone in the world is diagnosed with dementia.
Depression and dementia in the age of COVID-19: Two sides, one coin
Every seven seconds, someone in the world is diagnosed with dementia. A typical case that I often see in my practice is as follows: A 76-year-old woman has a two-year history of progressive worsening of short-term memory and cognitive decline. She can’t recall the names of her grandchildren and is devastated by her deteriorating abilities. However, this is not the first time in her life that she has had feelings of loss and despair.
Anticonvulsant Effects of Sertraline: A Case Report
Anja Brennecke Anja Brennecke Affiliations Krembil Brain Institute, University Health Network, University of Toronto, 60 Leonard Avenue, Krembil Discovery Tower, Room 4KD477, Toronto, Ontario, M5T 2S8, Canada Search for articles by this author Donald F. Weaver Donald F. Weaver Correspondence Corresponding author.
The complex relationship between dementia and domestic violence
DEvery week in my neurology clinic, I see patients and their families who are dealing with the realities of dementia. Of the many people I encounter, these three stories highlight a growing health issue that I feel is neglected — the complex relationship between dementia and domestic violence. The first is a story of confusion: “Dad is a nice guy, always has been. But now, because of the Alzheimer’s, he’s confused most of the time — and Mom isn’t coping.
Dementia’s hidden darkness: Violence and domestic abuse
Every week in my neurology clinic, I see patients and their families who are dealing with the realities of dementia. Of the many people I encounter, these three stories highlight a growing health issue that I feel is neglected — the complex relationship between dementia and domestic violence. The third is a scene of abuse: “I got divorced a long time ago because he used to hit me … a lot. He would get drunk every Saturday night and beat me up. He even knocked me out cold, probably five or six times.
Dementia's hidden darkness: Violence and domestic abuse
Alarmingly, evidence now suggests that there may be a complex but definitive link between dementia and domestic abuse Published 10:00 AM, November 17, 2018 Updated 10:00 AM, November 17, 2018 REALITIES. Dementia patients are often the perpetrators and often the victims of abuse. Research also shows that a medical history of head injury can more than double the risk of developing Alzheimer’s disease in some populations, even after many years.
Dementia patients are often both the perpetrators and victims of abuse, research shows
Dementia patients are often the perpetrators and often the victims of abuse. Research also shows that a medical history of head injury can more than double the risk of developing Alzheimer’s disease in some populations, even after many years. Credit: Shutterstock Every week in my neurology clinic, I see patients and their families who are dealing with the realities of dementia.
The hidden variables problem in Alzheimer's disease clinical trial design
Extensive nutritional studies have established a role for diet in moderating the pathogenesis, symptoms, and progression of AD [2x[2]Creegan, R., Hunt, W., McManus, A., and Rainey-Smith, S.R. Diet, nutrients and metabolism: cogs in the wheel driving Alzheimer's disease pathology?. Br J Nutr. 2015; 113: 1499–1517 Google ScholarSee all References, 3x[3]Liu, Q. and Zhang, J. Lipid metabolism in Alzheimer's disease. Neurosci Bull. 2014; 30: 331–345 Google ScholarSee all References].
Violence and domestic abuse
Every week in my neurology clinic, I see patients and their families who are dealing with the realities of dementia. Of the many people I encounter, these three stories highlight a growing health issue that I feel is neglected — the complex relationship between dementia and domestic violence. The first is a story of confusion: “Dad is a nice guy, always has been. But now, because of the Alzheimer’s, he’s confused most of the time — and Mom isn’t coping.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Donald
Contact Donald, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack