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Abstract Sexual hormone receptors (SHRs) are essential for breast cancer (BCa) pathogenesis. BCa is a prevalent malignancy with high heterogeneity and high recurrence. Endocrine resistance remains a major clinical challenge. SHR-mediated transcription involves complex epigenetic, post-translational, and inter-receptor crosstalk, and dysregulation of these processes contributes to endocrine resistance.
Abstract Renal cell carcinoma (RCC) is a frequent malignancy of the urinary system with high mortality and morbidity. However, the molecular mechanisms underlying RCC progression are still largely unknown. In this study, we identified FOXA2, a pioneer transcription factor, as a driver oncogene for RCC.
Loading metrics Open Access Peer-reviewed Research Article Wongyu Lee, Dongjun Yang, Je Hyeok Oh Wongyu Lee, Dongjun Yang, Je Hyeok Oh Published: March 24, 2020 https://doi.org/10.1371/journal.pone.0230687 Figures Abstract Aim This study was conducted to investigate the effect of resuscitation guideline terminology on the performance of infant cardiopulmonary resuscitation (CPR).
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