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Donnell Creel

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Safety and Effects of Gildeuretinol Acetate on Retinal Atrophic Lesions in Stargardt Disease : The TEASE-1 Randomized Clinical Trial

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By Leonide Saad, Neil M. Bressler, Stephen Tsang, Kimberly Stepien, Paul S. Bernstein, Byron Lam, Ilyas Washington, Michael Gorin, Hendrik P. N. Scholl, Mandeep Singh, Shazia Khan, Mary Frey, Sarah Justus, Sophia Park, Christine Xu, Thomas R. Connor, Dennis P. Han, Judy E. Kim, David Weinberg, William Wirostko, Kurt Pfeifer, Heather L. Toth, Patricia L. Winter, Hannah Sheppard, Amanda Daubert, Potyra Rosa, Elizabeth Nuttall, William Hubbard, Melissa Chandler, Becky Weeks, Anna Matynia, Gabrielle DeBartolomeo, Arsany Makkar, Mahmood Seyd Shah, Robert L. Roseman, Kaushik M. Hazariwala, Krissa Packard, Eleanor Dorsey Veh, Vesper Williams, Kaitlin McKenney, Brittany Rego, Stephanie Moebius, Angela Urmanski, Senad Novic, Kimberley Wegner, Kelliann Farnsworth Ordonez, Donnell Creel, Steven Nusinowitz, Emma Stackpole, Julliane Bacerdo
| JAMA Network Verified
Introduction Stargardt disease (STGD) is an autosomal recessive macular dystrophy with a prevalence of 1 in 6000 to 1 in 10 000, characterized by retinal atrophic lesions, also known as chorioretinal atrophy, involving loss of photoreceptors, retinal pigment epithelium (RPE), and underlying choriocapillaris.1-3 Retinal atrophic lesions cause profound visual disturbances and progressive vision loss, including declines in visual acuity, visual fields, and night vision, as well as chromatopsia,...
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