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Dora Barbosa on Muck Rack

Dora Barbosa

As seen in: BioRxiv
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Articles

Actionable biological programs to enhance EGFR-targeted therapy response unveiled by single-cell lineage tracing in clinically relevant lung cancer models

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By Beatrice Gini, Whitney Tamaki, Johnny Yu, Dora Barbosa
| BioRxiv
Abstract Developing high-resolution approaches to capture both tumor architectural clonality and transcriptional state(s) in individual cells within heterogeneous tumor cell populations could shed light on the evolution of pre-existing and newly emergent tumor subclones and their phenotypes, elucidating their trajectories in response to selective pressures such as drug treatment.
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