Dorothy Barthélemy

Abstract Exposure to space environment disrupts the sensorimotor system due to adaptation to microgravity, leading to spatial disorientation, impaired coordination, and reduced postural control upon return to Earth. To simulate these effects, a six‑degree head‑down bed rest (HDBR) protocol was used. This randomized controlled trial examined whether exercise could mitigate declines in standing balance control following 14 days of HDBR.

2. Materials and Methods Protocol and registration: This scoping review was informed by the Joanna Briggs Institute methodology [19]. As such, Preferred Reporting Items for Systematic Reviews and meta-analyses (PRISMA ScR) guidelines were followed to redact this systematic scoping review [20,21]. There was no a priori protocol published, because it was not recommended at the time of the beginning of the study.